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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTTN
All Species:
19.7
Human Site:
S458
Identified Species:
39.39
UniProt:
Q14247
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14247
NP_005222.2
550
61586
S458
A
D
Y
R
E
A
S
S
Q
Q
G
L
A
Y
A
Chimpanzee
Pan troglodytes
XP_508613
542
59878
S450
A
D
Y
R
E
A
S
S
Q
Q
G
L
A
Y
A
Rhesus Macaque
Macaca mulatta
XP_001100193
550
61624
S458
A
D
Y
R
E
A
G
S
Q
Q
G
L
A
Y
A
Dog
Lupus familis
XP_851317
541
60553
S449
A
D
Y
Q
D
A
S
S
Q
Q
G
L
A
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60598
546
61241
S454
A
G
I
P
E
A
G
S
Q
Q
G
L
T
Y
T
Rat
Rattus norvegicus
Q9JHL4
436
48594
T348
E
V
P
S
E
Q
E
T
L
Y
E
E
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507265
462
52591
L374
E
A
I
S
Q
Q
E
L
A
Y
E
P
E
T
V
Chicken
Gallus gallus
Q01406
563
63311
S471
S
D
Y
Q
E
A
V
S
Q
R
E
A
E
Y
E
Frog
Xenopus laevis
Q6GM14
376
42749
N288
A
S
Q
Q
E
E
E
N
I
Y
Q
D
A
T
E
Zebra Danio
Brachydanio rerio
NP_001004121
504
56595
A415
V
Y
E
L
E
Q
H
A
A
E
H
T
H
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU84
531
58711
Q438
K
V
S
V
T
V
Q
Q
S
Q
S
V
K
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999782
587
64904
E493
M
G
Q
Q
T
Y
E
E
V
D
R
A
P
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
98.3
90.5
N.A.
92.1
23.8
N.A.
64.9
83.4
26.7
68
N.A.
21.4
N.A.
N.A.
46.5
Protein Similarity:
100
91
99
94.1
N.A.
95
40.1
N.A.
74.1
90
41.2
80
N.A.
38
N.A.
N.A.
59.8
P-Site Identity:
100
100
93.3
86.6
N.A.
60
6.6
N.A.
0
46.6
20
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
60
13.3
N.A.
6.6
66.6
33.3
20
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
9
0
0
0
50
0
9
17
0
0
17
42
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
0
0
9
0
0
0
0
9
0
9
0
0
0
% D
% Glu:
17
0
9
0
67
9
34
9
0
9
25
9
17
9
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
0
0
17
0
0
0
42
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
9
0
9
0
0
% H
% Ile:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
9
0
0
0
9
9
0
0
42
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
9
0
0
0
0
0
0
0
9
17
9
9
% P
% Gln:
0
0
17
34
9
25
9
9
50
50
9
0
0
0
0
% Q
% Arg:
0
0
0
25
0
0
0
0
0
9
9
0
0
0
0
% R
% Ser:
9
9
9
17
0
0
25
50
9
0
9
0
0
9
9
% S
% Thr:
0
0
0
0
17
0
0
9
0
0
0
9
9
17
9
% T
% Val:
9
17
0
9
0
9
9
0
9
0
0
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
42
0
0
9
0
0
0
25
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _